منابع مشابه
Improved Synthesis of Vasicinone
A new, high yielding method for the preparation of vasicinone (7) is described. Reaction of 2-nitrobenzoic acid with N, N¢-carbonyldiimidazole followed by 2-pyrrolidinone gave 1-(2-nitrobenzoyl)pyrrolidine-2-one (3). Reduction of the latter with 10% Pd-C afforded deoxyvasicinone (4). Reaction of deoxyvasicinone (4) with bromine yielded monobromo-deoxyvasicinone (5). Exchange of bro...
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ژورنال
عنوان ژورنال: The Lancet
سال: 1833
ISSN: 0140-6736
DOI: 10.1016/s0140-6736(02)95540-6